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microRNA as Biomarkers and Diagnostics
17 March, 2014 - 18 March, 2014 Omni Parker House, Boston, MA, USA


microRNA as Biomarkers and Diagnostics Conference





Recent research has shown microRNAs to have tremendous potential as non-invasive biomarkers for the diagnosis and prognosis of disease, monitoring of treatment, and patient stratification, with exosome-derived microRNAs of particular interest. Cambridge Healthtech Institute's Tenth AnnualmicroRNA as Biomarkers and Diagnostics will cover the latest developments in the use of microRNA in the early detection of disease for more effective treatment, monitoring tumor growth and disease progression, issues associated with microRNA measurement, and the potential for personalized medicine based on microRNA profile.

Coverage Includes:

microRNA Biomarkers in Drug Development

microRNA Biomarkers as Cancer Diagnostics

microRNA as Disease Biomarkers


Featured Speakers:

Philippe CouttetPhilippe Couttet

Head, Pathway Integration Discovery

Novartis Pharma AG

Pavan KumarPavan Kumar

Senior Scientist, Biomarkers and Personalized Medicine

Eisai

Rounak NassirpourRounak Nassirpour

Principal Scientist, Drug Safety R&D

Pfizer

James FallsJames G. Falls

Manager, Discovery and Molecular Toxicology

GlaxoSmithKline


Pre-Conference Short Course*

March 17, 2014, 9:00 am-12:00 pm

Long Non-Coding RNAs as Biomarkers

Instructors:

Dave S. B. Hoon, Ph.D., Director, Molecular Oncology, John Wayne Cancer Institute

Jingfang Ju, Ph.D., Associate Professor, Co-Director of Translational Research, Pathology, Stony Brook University



Dinner Course*

March 17, 2014, 6:00-9:00 pm

Exosomal microRNAs as Non-Invasive Biomarkers

MicroRNAs encapsulated in exosomes are stable in body fluids and may serve as novel biomarkers for:

  • Early detection of disease
  • Determination of treatment options
  • Disease prognosis

Instructors to be Announced

* Separate Registration Required


Utility of microRNA Biomarkers in Drug Development

MicroRNAs as Genomic Indicators of Cardiotoxicity

Philippe Couttet, Ph.D., Head, Pathway Integration Discovery and Investigative Safety, Novartis Pharma AG

Circulating miRNAs as Potential Biomarkers for Cardiovascular Toxicity

James G. Falls, Ph.D., Manager, Discovery and Molecular Toxicology, GlaxoSmithKline

MicroRNAs as Promising Biomarkers of Renal Injury

Rounak Nassirpour, Ph.D., Principal Scientist, Investigative Pathology Laboratory, Drug Safety
R&D, Pfizer

MiRNAs as Circulating Biomarkers for Alzheimer's Disease

Pavan Kumar, Ph.D., Senior Scientist, Biomarkers and Personalized Medicine, Eisai

MicroRNAs Downregulated in Drug-Resistant Cancer Cells as Biomarkers and Therapeutic Targets for Drug Efficacy

Taosheng Chen, Ph.D., Associate Member and Director of HTS, Chemical Biology and Therapeutics, St. Jude Children's Research Hospital

microRNA Biomarkers as Cancer Diagnostics

microRNA Biomarkers as Cancer Diagnostics

Advancing Molecular Diagnostics and Precision Medicine Using Non-Coding RNA Variants

Prasun J. Mishra, Ph.D., Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH

Tissue Slide-Based microRNA Diagnostics for Cancer Medicine

Lorenzo F. Sempere, Ph.D., Research Assistant Professor, Medicine, Geisel School of Medicine, Dartmouth-Hitchcock Medical Center

MicroRNAs as Predictive and Prognostic Biomarkers in Colorectal Cancer

Jingfang Ju, Ph.D., Associate Professor, Co-Director of Translational Research, Pathology, Stony Brook University

Circulating Exosomal RNA as Diagnostic Markers and Real-Time Therapeutic Markers for Cancer

Douglas D. Taylor, Ph.D., Professor, Obstetrics, Gynecology, and Women's Health, University of Louisville School of Medicine

MicroRNAs as Central Players in the Biology of the Tumor Microenvironment: When Decoding miRNA Riddles Leads to Personalized Medicine

Muller Fabbri, M.D., Ph.D., Assistant Professor, Pediatrics and Molecular Microbiology & Immunology, University of Southern California Keck School of Medicine, Children's Hospital Los Angeles


microRNA as Disease Biomarkers

Talk Title to be Announced

Zachary Zimmerman, Ph.D., Senior Director, Corporate Development, Regulus Therapeutics

Hepatitis C Virus-Induced Modulation of Host microRNAs Is No miRage: Novel Biomarkers for Liver Disease

John Paul Pezacki, Ph.D., Senior Research Officer and Group Leader, Life Sciences, National Research Council of Canada

Urinary miRNA Patterns in Type 1 Diabetes: Implications for Prognosis and Pathogenesis of Diabetic Nephropathy

John P. Johnson, M.D., Professor, Medicine, Cell Biology and Physiology, University of Pittsburgh

Christos Argyropoulos, M.D., Ph.D., Medical Affairs Consultant

Circulating microRNAs in Plasma as Predictive Biomarkers for Parkinson's Disease: A New Paradigm

Sok Kean Khoo, Ph.D., Distinguished Associate Professor, Molecular Genomics, Department of Cell & Molecular Biology, GVSU Michigan


Problem-Solving Breakout Discussions with Expert Moderators

  • How to Choose a microRNA Normalization Strategy
  • Detection of Circulating microRNAs
  • microRNA Analysis in Tissue Specimens

* The program is subject to change without notice, due to unforeseen reason.



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