Cambridge Healthtech Institute’s 7th Annual

Optimizing Expression Platforms

Employment and Development of Cells, Process, and Personnel to Efficiently Produce Biotherapeutics

January 23-24, 2020

Part of the Biotherapeutic Expression & Production pipeline

The utilization of engineered therapeutic proteins for basic research, clinical diagnostics, and therapy continues to expand. Consequently, protein expression laboratory managers and researchers face challenges for efficient expression, production, and purification, even while improving quantity and quality, plus minimizing time and cost. Transient protein production (TPP) has the advantage of speed and limited risk, while stable transfection – the longer and more complex process – has the advantage of being able to produce long-term expression of the biotherapeutic of interest. Cambridge Healthtech Institute’s 7th Annual Optimizing Expression Platforms conference convenes protein expression experts to share their day-to-day challenges in high-throughput production and purification labs and provide insights and solutions on meeting these challenges. 

Preliminary Agenda


Reducing Recombinant Protein Expression During CHO Pool Selection Enhances Pool Productivity and the Frequency of High-Producing Cells
Yves Durocher, PhD, Head, Mammalian Cell Expression, National Research Council Canada

Multi-Omics Profiling of CHO Parental Hosts Reveals Cell Line-Specific Variations in Bioprocessing Traits

Meiyappan Lakshmanan, PhD, Research Scientist & Group Leader, Systems Biology, Bioprocessing Technology Institute, A*STAR

Transient expression and production

A Transient Platform Optimized to Suit Antibody Development Needs

Sarah Barker, PhD, Director, Product Development, C-Lab Management Team, Centre for the Commercialization of Antibodies and Biologics (CCAB)


Managing Core Facilities
Bjørn Voldborg, MSc, Director, CHO Cell Line Development, The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark

Balancing Platform Delivery, Innovation, and Job Satisfaction in the HT Protein Production Space
Edward Kraft, PhD, Senior Scientific Manager, High Throughput Protein Production, Genentech, Inc.


* The program is subject to change without notice, due to unforeseen reason.

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